Search results for "Phytopathogenic fungi"

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Identification of Novel Hexapeptides Bioactive against Phytopathogenic Fungi through Screening of a Synthetic Peptide Combinatorial Library

2002

The purpose of the present study was to improve the antifungal activity against selected phytopathogenic fungi of the previously identified hexapeptide PAF19. We describe some properties of a set of novel synthetic hexapeptides whose D-amino acid sequences were obtained through screening of a synthetic peptide combinatorial library in a positional scanning format. As a result of the screening, 12 putative bioactive peptides were identified, synthesized, and assayed. The peptides PAF26 (Ac-rkkwfw-NH(2)), PAF32 (Ac-rkwhfw-NH(2)), and PAF34 (Ac-rkwlfw-NH(2)) showed stronger activity than PAF19 against isolates of Penicillium digitatum, Penicillium italicum, and Botrytis cinerea. PAF26 and PAF3…

Antifungal AgentsMicrobial Sensitivity TestsApplied Microbiology and BiotechnologyMelittinPenicillium italicumMicrobiologyAntifungal peptidechemistry.chemical_compoundFusariumPeptide LibraryFusarium oxysporummedicineEnzymology and Protein EngineeringPeptide libraryPhytopathogenic fungiPlant DiseasesBotrytis cinereaPenicillium digitatumEcologybiologyPenicilliumfood and beveragesBiological activitybiology.organism_classificationmedicine.drug_formulation_ingredientBiochemistrychemistryPenicillium expansumPeptidesOligopeptidesHexapeptide PAF19Food ScienceBiotechnology
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Community Composition, Antifungal Activity and Chemical Analyses of Ant-Derived Actinobacteria

2020

Actinobacteria associated with insects represent one potentially rich source of novel natural products with antifungal activity. Here, we investigated the phylogenetic diversity and community composition of actinobacteria associated with ants using a combination of culture-dependent and -independent methods. Further, we assessed the antagonistic activity against phytopathogenic fungi and identified the secondary metabolites from isolates with bioactivity. A total of 416 actinobacterial isolates were obtained from three ant species (Camponotus japonicus, Lasius fuliginosus, and Lasius flavus) located in five nests. The largest amount of isolates were observed in the head samples. 16S rRNA ge…

Microbiology (medical)lcsh:QR1-502StreptomycesMicrobiologylcsh:MicrobiologyActinobacteriahigh throughput sequencing03 medical and health sciencesIntrasporangiaceaeDermacoccaceaeBotanyCamponotus japonicusphytopathogenic fungi030304 developmental biologyOriginal Research0303 health sciencesbiologyactinobacterial community030306 microbiologyStreptomycetaceaeLasiusantifungal activitybiology.organism_classificationNocardiaceaeant-derived actinobacteriaagroactive compoundFrontiers in Microbiology
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